Institute of Chemistry of the Academy of Sciences of Moldova
Larisa Postolachi
chemjm_correspondence@yahoo.com
mEDRA
20161225
07
10.19261/cjm.2016.11(1).10
http://www.cjm.asm.md/sites/default/files/article_files/ChemJMold201611(1)_74-85_Siaka.pdf
Institute of Chemistry of the Academy of Sciences of Moldova
mEDRA
01
Chemistry Journal of Moldova
05
ChemJMold
01
Institute of Chemistry of the Academy of Sciences of Moldova
MD
07
1857-1727
JB
07
2345-1688
JD
11
1
June 2016
01
201606
10
11
74
85
12
01
DFT (B3LYP) Computational Study on the Mechanisms of Formation of Some Semicarbazones
1
A01
Abdulfatai Siaka
Siaka, Abdulfatai
Abdulfatai
Siaka
2
A01
Adamu Uzairu
Uzairu, Adamu
Adamu
Uzairu
3
A01
Sulaiman Idris
Idris, Sulaiman
Sulaiman
Idris
4
A01
Hamza Abba
Abba, Hamza
Hamza
Abba
01
eng
20
semicarbazone; kinetics; bi- and unimolecular step; transition step; spontaneity
01
Thermodynamic and kinetic mechanisms of forming six semicarbazones have been investigated computationally by DFT B3LYP method. All the reactions proceed via two transitions and include two consecutive steps: bimolecular and unimolecular. The computed transition steps have varying equilibrium constants values, enthalpy of activation and Gibbs energy of activation, depending on the semicarbazone involved.
201606
2016
Institute of Chemistry of the Academy of Sciences of Moldova
Macroscale and Microscale Organic Experiments
9780395902202
Williamson, K.L.
1999
Cerecetto, H.; González, M. Current Topics in Medicinal chemistry, Chemotherapy of chagas’ disease: status and new development. Current Topics in Medicinal Chemistry, 2002, 2, pp. 1185-1190
10.1016/j.farmac.2004.11.012
10.1021/jm050283b
Mishra, V.; Pandeya, S.N. Analgesic activity and hypnotic effect of (±)-3-mentone semicarbazone and thiosemicarbazone derivatives. Acta Pharmaceutica, 2001, 51, pp. 183-188
Singhal, M.; Paul, A.; Singh, H.P.; Dubey, S.K.; Gaur, K. Evaluation of reducing power assay of chalcone semicarbazones. Journal of Chemical and Pharmaceutical Research, 2011, 3, pp. 639-645
Rajasekaran, S.; GopalKrishna R.; Sanjay Pai, P.N.; Gurpreet, S.S. Synthesis, Antibacterial and in vitro Antioxidant Activity of 2,3-Substituted Quinazolin-4(3H)-ones. Journal of Chemical and Pharmaceutical Research, 2010, 2, pp. 482-488
10.1021/jm9603025
10.1006/phrs.1997.0250
Pandeya, S.N.; Mishra, V.; Ponnilavarasan, I.; Stables, J.P. Anticonvulsant activity of p-chlorophenyl substituted arylsemicarbazones – the role of primary terminal amino group. Polish Journal of Pharmacology, 2000, 52, pp. 283-290
Pandeya, S.N.; Sowmayalakshmi, V.; Panda, S.S.; Pandey, A.; Stable, J.P. Anticonvulsant activity of semicarbazone derivatives of Mannich bases. Indian Journal of Chemistry, 2003, 42, pp. 2657-2661
Physical Chemistry
9780805338423
Engel, T.
2006