Chemistry Journal of Moldova

MALDI-TOF INVESTIGATION OF LYSOZYME-ALBUMIN INTERACTION

Author(s):

Marharyta Vasylieva, Taras Gromovoy


Field: Physical chemistry and chemical physics
Type: Short communication
Issue: 2014 Volume 9, no.2
Pages: 107-110
Keywords:

MALDI-TOF, albumin, lysozyme, protein-protein interaction


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DOI:
dx.doi.org/10.19261/cjm.2014.09(2).15

Graphical Abstract: 
Proteins are the main components of living systems therefore they are a subject of study from different points of view. Under certain conditions, proteins are capable of self-organization forming oligomeric structures of various composition and new properties. The investigations of these transformations were carried out on two well known proteins: albumin and lyzozyme. It is shown that associates of albumin and lysozyme are formining in the stoichiometric ratios of 1:1, 1:2, 1:3, 1:4. A similar pattern is observed in the case of albumin dimer.




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