Chemistry Journal of Moldova

Natural product chemistry and synthesis

TARGET-ORIENTED SYNTHESIS OF SOME TERPENOIDS OF MARINE ORIGIN

Author(s):

Nicon Ungur


Field: Natural product chemistry and synthesis
Type: Short communication
Issue: 2011 Volume 6, no.2
Pages: 30-35
Keywords: marine natural products, terpenoids; glycerol; scalaranes, cheilanthanes, sesterterpenoids, cyclizations, superacids, rearrangements, synthesis.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2011.06(2).08

Graphical Abstract:
 The paper presents an outline of the synthesis of some natural terpenoids of marine origine having diverse carbocyclic skeletons: labdanic, isocopalic, scalaranic, cheilanthanic, drimanic, sacculatanic. Schemes – 6, figures - 2. Bibliographic references – 35.

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SYNTHESIS AND PHOTOOXYGENATION OF THE METHYL ESTER OF 11-HOMODRIM-6,8(9)-DIENE-12-OIC ACID

Author(s):

Biriiac Andrei


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2011 Volume 6, no.2
Pages: 79-83
Keywords: homodrimanes, synthesis, photooxygenation.
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ON THE PECULIARITIES OF THE RING CONTRACTION REACTIONS OF HOMODRIMANES VIA ACID MEDIATED EPOXIDE REARRANGEMENT

Author(s):

Veaceslav Kulciţki, Tatiana Sîrbu, Nicon Ungur


Field: Natural product chemistry and synthesis
Type: Short communication
Issue: 2011 Volume 6, no.1
Pages: 110-112
Keywords: terpenoids, homodrimane, epoxide, rearrangement, hydrindane.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2011.06(1).02

Graphical Abstract: 
A selective rearrangement of a epoxy-homodrimanic substrate is described. Using fluorosulfonic acid at low temperature leads by ring contraction to a perhydrindanic structure. On the contrary, using boron trifluoride-diethyl ether at r.t. selectively brings about angular methyl migration.

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OCCURRENCE AND CHEMISTRY OF DIHYDROXYFUMARIC ACID

Author(s):

N. Secara, Gh. Duca, L. Vlad, F. Macaev


Field: Natural product chemistry and synthesis
Type: Review
Issue: 2011 Volume 6, no.1
Pages: 29-44
Keywords: dihydroxyfumaric acid, fluorescent sensors, molecular clips, coordination polymers.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2011.06(1).14

Graphical Abstract:


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SYNTHESIS OF NITROGEN-CONTAINING COMPOUNDS FROM HIGHER TERPENOIDS

Author(s):

Aculina Aricu


Field: Natural product chemistry and synthesis
Type: Review
Issue: 2011 Volume 6, no.1
Pages: 10-28
Keywords: synthesis, nitrogen-containing compounds, terpenoids, Beckmann rearrangement.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2011.06(1).15

Graphical Abstract:
The presence of nitrogen in the molecule is usually accompanied either by the appearance of a new activity or the intensification of original activity characteristic for the native terpenoids. This maintains alive the scientific interest in the synthesis of such compounds. The present communication put into discussion the recently elaborated  methods for preparation of the nitrogen-containing terpenic compounds.


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ON SOME PECULIARITIES OF ETHYL 5-HYDROXY-1,2-DIMETHYL-1H-3-INDOLECARBOXYLATE SYNTHESIS

Author(s):

Felix Shepel, Diana Shepel, Fliur Macaev


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 116-117
Keywords: derivatives of 5-oxindole, cardio-vascular remedies.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).01

Graphical Abstract: 
It has been conducted increase the yield up to 63% of ethyl 5-hydroxy-1,2-dimethyl-1H-3-indolecarboxylate via interaction of p-benzoquinone with N-methyl-b-aminocrotone ether in mixture of glacial acetic acid/ethyl acetate.
 


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NEW EFFECTIVE SYNTHESYS OF CHINCHONINIC ACIDS FROM (-)-Α-PINENE

Author(s):

Oleg Radul, Alexandru Gudima, Fliur Macaev


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 78-81
Keywords: chinchoninic acids, quinoline, pinonic acid, α-pinene.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).07

Graphical Abstract: 
New effective synthesis of the chiral chinchoninic acids form (-)-α-pinene has been elaborated. It has been shown that, the considerable increase of the yield and purity of chiral acids is achieved applying the method of under phase transfer catalysis. New effective synthesis of the chiral chinchoninic acids form (-)-α-pinene has been elaborated. It has been shown that, the considerable increase of the yield and purity of chiral acids is achieved applying the method of under phase transfer catalysis.


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STEROIDAL GLYCOSIDES FROM THE ROOTS OF SOLANUM MELONGENA L.

Author(s):

Stepan Shvets, Irina Nedova, Pavel Kintia, Carla Bassarelo, Cosimo Pizza and Sonia Piacente


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 72-77
Keywords: steroidal glycoside, NMR analysis, Solanum melongena L.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).08

Graphical Abstract:
 One new cholestane glycoside, six steroidal glycosides of spirostane series and one pregnane glycoside have been isolated from the roots of Solanum melongena L. for the first time. Their structures were determined by physico-chemical methods.

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(-)-DRIMENOL – A VALUABLE STARTING COMPOUND FOR THE SYNTHESIS OF DRIMANIC SESQUITERPENOIDS

Author(s):

Aculina Aricu


Field: Natural product chemistry and synthesis
Type: Review
Issue: 2009 Volume 4, no.2
Pages: 14-23
Keywords: drimenol, albicanol, drimenyl acetate, polygodial, warburganal, synthesis.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).17

Graphical Abstract:
 (-)-Drimenol is a relatively accessible compound, that has been and may be further used as a starting material to prepare sesquiterpenoids. The present review deals with the methods of obtaining of this compound as well as its usage.

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ISOLATION OF ENT-KAUR-16-EN-19-OIC AND ENT-TRACHILOBAN-19-OIC ACIDS FROM THE SUNFLOWER HELIANTHUS ANNUUS L.DRY WASTE

Author(s):

Nicon Ungur, Marina Grinco, Veaceslav Kulciţki, Alic Barba, Tatiana Bîzîcci, Pavel F. Vlad


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2008 Volume 3, no.2
Pages: 105-108
Keywords: ent-kaur-16-en-19-oic acid, ent-trachiloban-19-oic acid, diterpene, isolation.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2008.03(2).01

Graphical Abstract:
 A relatively simple method for isolation of the mixture of ent-kaur-16-en-19-oic (1) and ent-trachiloban-19-oic (2) acids from dry waste of sunflower processing has been elaborated, and it has been shown that the waste can serve as an accessible source of ent-kauranic and ent-trachilobanic diterpenoids.

Downloads: 33