Chemistry Journal of Moldova

2009 Volume 4, no.2

ON SOME PECULIARITIES OF ETHYL 5-HYDROXY-1,2-DIMETHYL-1H-3-INDOLECARBOXYLATE SYNTHESIS

Author(s):

Felix Shepel, Diana Shepel, Fliur Macaev


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 116-117
Keywords: derivatives of 5-oxindole, cardio-vascular remedies.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).01

Graphical Abstract: 
It has been conducted increase the yield up to 63% of ethyl 5-hydroxy-1,2-dimethyl-1H-3-indolecarboxylate via interaction of p-benzoquinone with N-methyl-b-aminocrotone ether in mixture of glacial acetic acid/ethyl acetate.
 


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IMPLICATIONS OF GLOBAL AND LOCAL MOBILITY IN AMORPHOUS EXCIPIENTS AS DETERMINED BY DSC AND TM DSC

Author(s):

Ion Dranca, Tudor Lupascu


Field: Physical chemistry and chemical physics
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 105-115
Keywords: molecular mobility; excipients (sucrose & trehalose); α- and β-relaxations; activation energy; DSC & TM DSC.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).02

Graphical Abstract:
 The paper explores the use of differential scanning calorimetry (DSC) and temperature modulated differential scanning calorimetry (TM DSC) to study α- and β- processes in amorphous sucrose and trehalose. The real part of the complex heat capacity is evaluated at the frequencies, f, from 5 to 20mHz. β-relaxations were studied by annealing glassy samples at different temperatures and subsequently heating at different rates in a differential scanning calorimeter.

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HYBRID ORGANIC-INORGANIC COMPOSITE MATERIALS FOR APPLICATION IN CHEMICAL SENSORS

Author(s):

Anca-Dana Bendrea, Ana-Maria Catargiu and Mircea Grigoras


Field: Supramolecular chemistry
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 100-104
Keywords: polymers composites, SBA-polithiophene, SBA-polyaniline.
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DOI:
dx.doi.org/10.19261/cjm.2009.04(2).03

Graphical Abstract:



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USE OF ELECTROSPRAY MASS SPECTROMTERY TO STUDY THE INTERACTIONS BETWEEN PARA-SULPHONATO-CALIX[4]ARENE AND A SERIES OF SERUM ALBUMIN PROTEINS

Author(s):

Jalil Moubarak, Elodie Moreno, Eric Diesis and Anthony W. Coleman


Field: Supramolecular chemistry
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 94-99
Keywords: Calix[n]arene, para-Sulphonato-calix[4]arene, Electrospray Mass Spectrometry, Binding Constants, Complex Stoichiometry, Sequential Binding.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).04

Graphical Abstract: 
The binding of para-Sulphonato-calix[4]arene to a series of Serum Albumin Proteins has been studied using Electrospray Mass Spectrometry, each protein shows different capacities to interact with para-Sulphonato-calix[4]arene, including the number of ligands bound, the Association Constants observed, and the stoichiometries at which the onset of each binding event is observed.

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THE SOLID-STATE INCLUSION COMPLEX BETWEEN THE MONO-ANION OF CALIX[4]ARENE AND PROTONATED DIAMINO-BICYCLOUNDECANE

Author(s):

Oleksandr Shkurenko, Kinga Suwinska, Florent Perret, Katia Sigaud, Antoine Leydier, Said Jebors and Anthony W. Coleman


Field: Supramolecular chemistry
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 86-93
Keywords: Calix[n]arenes, X-ray Crystallography, Structure, Mono-anionic, Diamino-Bicycloundecane, inclusion polymer.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).05

Graphical Abstract:
 Diamino-bicycloundecane mono-deprotonates H-calix[4]arene and the solid-structure of the resulting salt has been determined by X-ray crystallography. Two different complexes are present in the structure with the Diamino-bicycloundecane cation held in the calix[4]arene cavity by CH-p interactions. In the packing there is a hydrogen-bonded polymeric chain. Both the complexes formed layered structures with differing inter-layer distances. 

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FLUORESCENT N-HETEROCYCLES VIA ONE-POT TANDEM REACTIONS

Author(s):

Rodica Dinica, Bianca Furdui, Geta Cârâc and Constantin Stanciu


Field: Organic chemistry
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 82-85
Keywords: microwave, “one-pot” reaction, indolizine.
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DOI:
dx.doi.org/10.19261/cjm.2009.04(2).06

Graphical Abstract:
 Substituted indolizines are very attractive heterocyclic units. On developing efficient methods toward differently substituted indolizines, we were particularly interested in elaborating efficient approaches toward three-component reaction of these compounds which are very interested from the point of view fluorescent properties. The microwave-mediated three component reaction of acyl bromide, bipyridine and dipolarophyl is catalyzed by basic alumina to give corresponding bis-indolizines in excellent yields in a one –pot reaction.

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NEW EFFECTIVE SYNTHESYS OF CHINCHONINIC ACIDS FROM (-)-Α-PINENE

Author(s):

Oleg Radul, Alexandru Gudima, Fliur Macaev


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 78-81
Keywords: chinchoninic acids, quinoline, pinonic acid, α-pinene.
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DOI:
dx.doi.org/10.19261/cjm.2009.04(2).07

Graphical Abstract: 
New effective synthesis of the chiral chinchoninic acids form (-)-α-pinene has been elaborated. It has been shown that, the considerable increase of the yield and purity of chiral acids is achieved applying the method of under phase transfer catalysis. New effective synthesis of the chiral chinchoninic acids form (-)-α-pinene has been elaborated. It has been shown that, the considerable increase of the yield and purity of chiral acids is achieved applying the method of under phase transfer catalysis.


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STEROIDAL GLYCOSIDES FROM THE ROOTS OF SOLANUM MELONGENA L.

Author(s):

Stepan Shvets, Irina Nedova, Pavel Kintia, Carla Bassarelo, Cosimo Pizza and Sonia Piacente


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 72-77
Keywords: steroidal glycoside, NMR analysis, Solanum melongena L.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).08

Graphical Abstract:
 One new cholestane glycoside, six steroidal glycosides of spirostane series and one pregnane glycoside have been isolated from the roots of Solanum melongena L. for the first time. Their structures were determined by physico-chemical methods.

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SYNTHESIS AND STUDY OF COMPLEXES OF COPPER(II), ZINC, COBALT(II) AND NICKEL(II) WITH NITROFLUORENYLIDENE-9-AMINO(IMINO) DERIVATIVES

Author(s):

S.B. Strashnova, O.V. Avramenko, M.N. Zhuk, O.V.Kovalchukova, P.V. Strashnov, B.E. Zaitsev


Field: Inorganic and coordination chemistry
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 68-71
Keywords: 3d metals; complexes; nitrofluoreniliden-9-anilin; amino-group.
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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2009.04(2).09

Graphical Abstract:
 The complexes of general formula MCl2∙L1-4nH2O (where L1 - N-(2,4,7-trinitrofluorenilidene-9)-p-dimethyl-aminoanilin, L2 - N-(2,4,5,7-tetranitrofluorenilidene-9)-p-dimethylaminoaniline, L3 N-(2,4,7-trinitrofluorenilidene)-N-(p-dimethylaminophenyl)hydroxylamine, L4 - N-(2,4,5,7-tetranitrofluorenilidene-9)-N-(p-dimethylaminophenyl)-hydroxylamine; M=Cu, Co, Ni, Zn; n= 1-3 have been synthesized and investigated by different methods. Spectral criteria of co-ordination of the molecules L1 –L4 in electronic adsorption spectra were detected.

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SYNTHESIS, CRYSTAL STRUCTURE AND MAGNETIC BEHAVIOUR OF NOVEL 4f-2s HETEROMETALIC ONE-DIMENSIONAL COORDINATION POLYMERS ON THE BASE OF 2-FURAN-CARBOXYLIC ACID

Author(s):

Silvia Melnic, Denis Prodius, Sergiu Shova, Helen Stoeckli-Evans, Yurii Simonov, Alexandr Feher, Maria Gdaniec, Constantin Turta


Field: Inorganic and coordination chemistry
Type: Research paper
Issue: 2009 Volume 4, no.2
Pages: 60-67
Keywords: heteronuclear lanthanide (III) complexes, furancarboxylates ligand, crystal structure, magnetic properties.
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DOI:
dx.doi.org/10.19261/cjm.2009.04(2).10

Graphical Abstract:
 Nine new complexes with the general formula {[Ln2Ba(α-Fur)8(H2O)4]}n, where Ln = Nd3+, Sm3+Eu3+, Pr3+, Gd3+, Tb3+, Ho3+, Er3+ and La3+; α-Fur ≡ C4H3OCOO, were synthesized and characterized by IR spectra, magnetism, X-ray single crystal and powder diffractions.

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