Chemistry Journal of Moldova

SYNTHESIS OF NEW HOMODRIMANE SESQUITERPENOIDS CONTAINING DIAZINE, 1,2,4-TRIAZOLE AND CARBAZOLE RINGS

Author(s):

Gheorghe Duca, Aculina Aricu, Lidia Lungu, Nadejda Tenu, Alexandru Ciocarlan, Yacob Gutu, Ion Dragalin, Alic Barba


Field: Organic chemistry
Type: Research paper
Issue: 2018 Volume 13, no.1
Pages: 69-73
Keywords:

sesquiterpenoids, N-substituted amides, heterocyclic amines, diazine, 1,2,4-triazole, carbazole, synthesis.


Full Text (PDF): Download

DOI:
http://dx.doi.org/10.19261/cjm.2017.458   

Abstract (PDF) 
Graphical Abstract: The study describes the synthesis of 11-homodrim-6,8-dien-12-oic acid N-substituted amides containing diazine, 1,2,4-triazole and carbazole rings based on commercially available sclareolide. The mentioned compounds were prepared for the first time by interaction of the generated in situ acyl chloride with some heterocyclic amines: 2- and 4-aminopyrimidine, 2-aminopyrazine, 3-amino-1,2,4-triazole and N-aminocarbazole. Their structures were fully elucidated by elemental and spectral analyses (IR, 1H and 13C NMR).


 

Downloads: 24