Chemistry Journal of Moldova

DEVELOPMENT AND VALIDATION OF AN ASSAY METHOD FOR CIPROFLOXACIN HYDROCHLORIDE DETERMINATION IN COMBINATION EAR DROPS

Author(s):

Livia Uncu, Elena Donici, Vladimir Valica, Oxana Vîslouh, Veaceslav Gonciar, Sergiu Parii


Field: Analytical chemistry
Type: Research paper
Issue: 2019 Volume 14, no.2
Pages: 56-61
Keywords:

ciprofloxacin hydrochloride, UV-Vis spectroscopy, validation, ear drop, Ocimum basilicum.


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DOI: http://dx.doi.org/10.19261/cjm.2019.607   
 
Abstract (PDF)
Graphical Abstract: A simple, precise and accurate UV-Vis spectrophotometric method has been developed and validated for the estimation of ciprofloxacin hydrochloride from combination ear drops with basil oil (Ocimum basilicum). The results of the validation of the method demonstrate that the developed method is simple, rapid, accurate and robust over the concentration range 2-10 μg/mL of ciprofloxacin hydrochloride in combination with volatile basil oil.


 

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